Chapter Six Glimpse into the Origin of Life
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چکیده
The ribosome is an essential universal cellular apparatus common to all life forms. This molecular assembly decodes the genetic information and catalyzes peptide bond formation. Analyses of all of the known threedimensional structures of ribosomes revealed that the major ribosomal functions are performed by the ribosomal RNA, in accordance with the suggestion that RNA existed before proteins. Careful examination of the conformations of the ribosomal functional sites revealed that the peptide bonds are being formed within a highly conserved pocket-like region, which seems to be a vestige of a prebiotic bonding entity, termed by us “the proto-ribosome”.
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تاریخ انتشار 2014